}}Denatonium, usually available as denatonium benzoate (under trade names such as Bitrex or Aversion) and as denatonium saccharide, is the most bitter compound known to date.It was discovered in 1958 during research on local anesthetics by Macfarlan Smith of Edinburgh, Scotland, and registered under the trademark Bitrex. Dilutions of as little as 10 ppm are unbearably bitter to most humans. Denatonium salts are usually colorless and odorless solids but are often traded as solutions. They are used as aversive agents to prevent accidental ingestion. Denatonium is used in denatured alcohol, antifreeze, nail biting preventions, animal repellents, liquid soaps, and shampoos. It is not known to pose any long-term health risks although exposure may be irritating and unpleasant.An amusing anecdote relates how one of the researchers at Atomergic Chemetals Corp. in Plainview, New York, went home without realising that he had a tiny trace of denatonium saccharide on th
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